Viral Aetiology in Adults with Acute Upper Respiratory Tract Infection in Jinan, Northern China
Open Access
- 1 January 2013
- journal article
- research article
- Published by Hindawi Limited in Journal of Immunology Research
- Vol. 2013, 1-7
- https://doi.org/10.1155/2013/869521
Abstract
Our study investigated the epidemiology of respiratory viruses in adult patients with upper respiratory tract infection (URTI) between August 2009 and September 2010 in Jinan, northern China. Nasal and throat swabs () were collected from adult patients with URTIs. Nine respiratory-related viruses, including IFV, PIV, HRV, HMPV, HBoV, HCoV, ADV, RSV, and EV, were detected in all samples by conventional and reverse transcription polymerase chain reactions. Positive detection rate for respiratory virus was 38.76% and codetection rate was 4.70% in adults with acute respiratory tract infections. IFV (20.81%) was the dominant agent detected and IFVB had a higher incidence (12.58%) than IFVA (7.72%). Detection rates of 8.22%, 5.03%, 3.69%, and 2.52% were observed for HBoV, HRV, EV, and RSV, respectively. HCoV had the lowest detection rate of 0.50%. HBoV, HRV, EV, and ADV infection rates were higher in the 14–25-year-old group than in the 26–65-year-old group. Codetection rates were higher (7.52%) in the 14–25-year-old group than in the older age group (2.64%). The spectrum of respiratory virus infection in adult patients with URTIs was different in Jinan compared with other cities in China.
Keywords
Funding Information
- China Central Government (2009ZX10004206-006, 2012ZX10004206-007, ZR2009CZ011)
This publication has 52 references indexed in Scilit:
- Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk predictionMolecular Psychiatry, 2012
- Etiology and Clinical Characterization of Respiratory Virus Infections in Adult Patients Attending an Emergency Department in BeijingPLOS ONE, 2012
- Detection of human bocavirus from children and adults with acute respiratory tract illness in Guangzhou, southern ChinaBMC Infectious Diseases, 2011
- Neuregulin 1 Promotes Excitatory Synapse Development and Function in GABAergic InterneuronsJournal of Neuroscience, 2011
- Human Bocaviruses Are Highly Diverse, Dispersed, Recombination Prone, and Prevalent in Enteric InfectionsThe Journal of Infectious Diseases, 2010
- Does schizophrenia arise from oxidative dysregulation of parvalbumin-interneurons in the developing cortex?Neuropharmacology, 2009
- Prolonged Exposure to NMDAR Antagonist Suppresses Inhibitory Synaptic Transmission in Prefrontal CortexJournal of Neurophysiology, 2008
- Maternal Immune Activation Alters Fetal Brain Development through Interleukin-6Journal of Neuroscience, 2007
- Severe Pneumonia and Human Bocavirus in AdultEmerging Infectious Diseases, 2006
- Human Bocavirus Infection, CanadaEmerging Infectious Diseases, 2006