Melatonin Biosynthesis in Drosophila: Its Nature and Its Effects
- 1 February 1988
- journal article
- Published by Wiley in Journal of Neurochemistry
- Vol. 50 (2), 382-387
- https://doi.org/10.1111/j.1471-4159.1988.tb02923.x
Abstract
Drosophila melanogaster homogenates incubated with tritiated 5-hydroxytryptophan, 5-hydroxytryptamine, or N-acetylserotonin have the ability of converting them into labelled indolamines, including melatonin. All these compounds were characterized by two-dimensional thin-layer chromatography by comparison with nonradiolabelled standards, and melatonin by mass spectrometry and radioimmunoassay. On the other hand, the injection of pharmacological doses of melatonin into 2-day-old female flies diminishes the mating speed and the oviposition rate.Keywords
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