Prognostic Factors for Recovery from Sudden Sensorineural Hearing Loss: A Retrospective Study
Open Access
- 30 April 2017
- journal article
- Published by The Korean Audiological Society in Journal of Audiology & Otology
- Vol. 21 (1), 9-15
- https://doi.org/10.7874/jao.2017.21.1.9
Abstract
This study aimed to investigate prognostic factors in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). From January 2007 to December 2011, a retrospective chart review identified 494 consecutive patients with ISSNHL. Demographic, audiometric, and clinical data were analyzed using a logistic regression test. Hearing recovery from ISSNHL was significantly associated with factors such as age, duration from onset of symptoms to commencement of treatment, severity of the initial pure tone threshold, and the treatment method. Intratympanic (IT) steroid administration alone showed a comparable efficiency to oral steroid administration with or without IT steroid injection. In patients who received IT steroid injection, the duration from onset to treatment, severity of initial hearing loss, and sequential IT steroid injection following systemic steroid administration were statistically associated with hearing improvement. Age, severity of initial pure tone threshold, duration from onset to treatment, initial speech discrimination, and initial pure tone threshold are statistically significant prognostic factors related to hearing improvement in ISSNHL. IT steroid injection as an initial single treatment is comparable to systemic oral steroid administration.Keywords
This publication has 34 references indexed in Scilit:
- Comparison of intermittent intratympanic steroid injection and near-continual transtympanic steroid perfusion as salvage treatments for sudden sensorineural hearing lossThe Laryngoscope, 2013
- Perilymph Pharmacokinetics of Markers and Dexamethasone Applied and Sampled at the Lateral Semi-Circular CanalJournal of the Association for Research in Otolaryngology, 2012
- Sudden Sensorineural Hearing LossTrends in Amplification, 2011
- Intratympanic Methylprednisolone Improves Hearing Function in Refractory Sudden Sensorineural Hearing Loss: A Control StudyAudiology and Neurotology, 2010
- Age-dependent changes in the expression of klotho protein, TRPV5 and TRPV6 in mouse inner earActa Oto-Laryngologica, 2009
- Age-dependent changes in the expression of klotho protein, TRPV5 and TRPV6 in mouse inner earActa Oto-Laryngologica, 2009
- Can Intratympanic Dexamethasone Added to Systemic Steroids Improve Hearing Outcome in Patients With Sudden Deafness?The Laryngoscope, 2008
- Idiopathic sudden sensorineural hearing loss: results drawn from the Swedish national databaseActa Oto-Laryngologica, 2007
- The Efficacy of Steroids in the Treatment of Idiopathic Sudden Hearing Loss: A Double-blind Clinical StudyJAMA Otolaryngology–Head & Neck Surgery, 1980
- Hair Cell Condition and Auditory Nerve Response in Normal and Noise-Damaged CochleasActa Oto-Laryngologica, 1979