Synthesis of a Chitosan−Dendrimer Hybrid and Its Biodegradation
- 19 July 2003
- journal article
- Published by American Chemical Society (ACS) in Biomacromolecules
- Vol. 4 (5), 1244-1249
- https://doi.org/10.1021/bm030021w
Abstract
Chitosan−dendrimer hybrids having various functional groups such as carboxyl, ester, and poly(ethylene glycol) groups were prepared successfully using dendrimer acetal by reductive N-alkylation. The synthetic procedure could be accomplished by one-step reaction without organic solvent. The degree of substitution of dendrimer was 0.13−0.18 evaluated by 1H NMR. A perfectly or partially water-soluble chitosan−dendrimer hybrid could be obtained. By standard activated sludge, good biodegradation was observed in these hybrids.Keywords
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