New solid forms of artemisinin obtained through cocrystallisation
- 31 August 2010
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in CrystEngComm
- Vol. 12 (12), 4038-4041
- https://doi.org/10.1039/c0ce00428f
Abstract
New solid forms of the important antimalarial artemisinin have been constructed by cocrystallisation; the difficulty of identifying successful cocrystals formers for artemisinin has been overcome through a mechanochemical screening procedure and the results are compared to predictions based on molecular descriptors obtained from the Cambridge Structural Database (CSD).Keywords
This publication has 30 references indexed in Scilit:
- Molecular Crystal Prediction Approach by Molecular Similarity: Data Mining on Molecular Aggregation Predictors and Crystal DescriptorsCrystal Growth & Design, 2009
- Pharmaceutical Cocrystals and Their Physicochemical PropertiesCrystal Growth & Design, 2009
- Qinghaosu (Artemisinin): The Price of SuccessScience, 2008
- Screening strategies based on solubility and solution composition generate pharmaceutically acceptable cocrystals of carbamazepineCrystEngComm, 2008
- Powder X-ray Diffraction as an Emerging Method to Structurally Characterize Organic SolidsOrganic Letters, 2007
- Pharmaceutical Cocrystals: An Emerging Approach to Physical Property EnhancementMRS Bulletin, 2006
- Pharmaceutical Co-CrystalsJournal of Pharmaceutical Sciences, 2006
- On substituents, steering, and stacking to control properties of the organic solid stateCrystEngComm, 2004
- Artemisinins target the SERCA of Plasmodium falciparumNature, 2003
- Supramolecular Synthons in Crystal Engineering—A New Organic SynthesisAngewandte Chemie, 1995