Membrane-bound α-synuclein interacts with glucocerebrosidase and inhibits enzyme activity
- 28 November 2012
- journal article
- Published by Elsevier BV in Molecular Genetics and Metabolism
- Vol. 108 (1), 56-64
- https://doi.org/10.1016/j.ymgme.2012.11.010
Abstract
No abstract availableKeywords
This publication has 61 references indexed in Scilit:
- Glucocerebrosidase deficiency in substantia nigra of parkinson disease brainsAnnals of Neurology, 2012
- Biophysics of α-synuclein membrane interactionsBiochimica et Biophysica Acta (BBA) - Biomembranes, 2012
- Depth of α-Synuclein in a Bilayer Determined by Fluorescence, Neutron Reflectometry, and ComputationBiophysical Journal, 2012
- A high throughput glucocerebrosidase assay using the natural substrate glucosylceramideAnalytical and Bioanalytical Chemistry, 2011
- Exploring the link between glucocerebrosidase mutations and parkinsonismTrends in Molecular Medicine, 2011
- Gaucher Disease Glucocerebrosidase and α-Synuclein Form a Bidirectional Pathogenic Loop in SynucleinopathiesCell, 2011
- Glucocerebrosidase is present in α-synuclein inclusions in Lewy body disordersActa Neuropathologica, 2010
- The Role of Glucocerebrosidase Mutations in Parkinson Disease and Lewy Body DisordersCurrent Neurology and Neuroscience Reports, 2010
- Multiple Tight Phospholipid-Binding Modes of α-Synuclein Revealed by Solution NMR SpectroscopyJournal of Molecular Biology, 2009
- The new mutation, E46K, of α‐synuclein causes parkinson and Lewy body dementiaAnnals of Neurology, 2003