Polymerase-Tailored Variations in the Water-Mediated and Substrate-Assisted Mechanism for Nucleotidyl Transfer: Insights from a Study of T7 DNA Polymerase
- 21 April 2009
- journal article
- Published by Elsevier BV in Journal of Molecular Biology
- Vol. 389 (4), 787-796
- https://doi.org/10.1016/j.jmb.2009.04.029
Abstract
No abstract availableThis publication has 57 references indexed in Scilit:
- Highly Dissociative and Concerted Mechanism for the Nicotinamide Cleavage Reaction in Sir2Tm Enzyme Suggested by Ab Initio QM/MM Molecular Dynamics SimulationsJournal of the American Chemical Society, 2008
- Quantum Mechanics/Molecular Mechanics Investigation of the Chemical Reaction in Dpo4 Reveals Water-Dependent Pathways and Requirements for Active Site ReorganizationJournal of the American Chemical Society, 2008
- Catalytic mechanism of human DNA polymerase λ with Mg2+ and Mn2+ from ab initio quantum mechanical/molecular mechanical studiesDNA Repair, 2008
- Lesion processing: high-fidelity versus lesion-bypass DNA polymerasesTrends in Biochemical Sciences, 2008
- How Do SET-Domain Protein Lysine Methyltransferases Achieve the Methylation State Specificity? Revisited by Ab Initio QM/MM Molecular Dynamics SimulationsJournal of the American Chemical Society, 2008
- The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerasesCell Research, 2008
- Ab Initio Quantum Mechanical/Molecular Mechanical Molecular Dynamics Simulation of Enzyme Catalysis: The Case of Histone Lysine Methyltransferase SET7/9The Journal of Physical Chemistry B, 2007
- A Water-Mediated and Substrate-Assisted Catalytic Mechanism forSulfolobus solfataricusDNA Polymerase IVJournal of the American Chemical Society, 2007
- Correct and incorrect nucleotide incorporation pathways in DNA polymerase βBiochemical and Biophysical Research Communications, 2006
- Magnesium-Induced Assembly of a Complete DNA Polymerase Catalytic ComplexStructure, 2006