Amplification of the c-myc gene and the elevation of its transcripts in human ovarian tumor lines.

Abstract

C-myc gene was amplified in the human ovarian tumor line OS-4 5-6-fold and in the OvCa-1 line 3-4-fold. The relative amount of the transcript from the c-myc gene to the total RNA in OS-4 was 6-fold that for normal cells.