Oncogenic Activity of Ect2 Is Regulated through Protein Kinase Cι-mediated Phosphorylation
Open Access
- 1 March 2011
- journal article
- Published by Elsevier BV
- Vol. 286 (10), 8149-8157
- https://doi.org/10.1074/jbc.m110.196113
Abstract
No abstract availableThis publication has 26 references indexed in Scilit:
- Diacylglycerol kinase α mediates HGF-induced Rac activation and membrane ruffling by regulating atypical PKC and RhoGDIProceedings of the National Academy of Sciences of the United States of America, 2010
- Ect2 links the PKCι–Par6α complex to Rac1 activation and cellular transformationOncogene, 2009
- The Guanine Nucleotide Exchange Factors Trio, Ect2, and Vav3 Mediate the Invasive Behavior of GlioblastomaThe American Journal of Pathology, 2008
- Matrix metalloproteinase-10 is a critical effector of protein kinase Cι-Par6α-mediated lung cancerOncogene, 2008
- Novel Functions of Ect2 in Polar Lamellipodia Formation and Polarity Maintenance during “Contractile Ring-Independent” Cytokinesis in Adherent CellsMolecular Biology of the Cell, 2008
- Inhibition of Cyclin-dependent Kinase 1 Induces Cytokinesis without Chromosome Segregation in an ECT2 and MgcRacGAP-dependent MannerPublished by Elsevier BV ,2005
- Requirement For C-terminal Sequences in Regulation of Ect2 Guanine Nucleotide Exchange Specificity and TransformationPublished by Elsevier BV ,2004
- Rho exchange factor ECT2 is induced by growth factors and regulates cytokinesis through the N‐terminal cell cycle regulator‐related domainsJournal of Cellular Biochemistry, 2003
- Human Ect2 Is an Exchange Factor for Rho Gtpases, Phosphorylated in G2/M Phases, and Involved in CytokinesisThe Journal of cell biology, 1999
- Oncogene ect2 is related to regulators of small GTP-binding proteinsNature, 1993