Acceptability of pre-exposure prophylaxis as an HIV prevention strategy: barriers and facilitators to pre-exposure prophylaxis uptake among at-risk Peruvian populations
- 1 May 2011
- journal article
- research article
- Published by SAGE Publications in International Journal of STD & AIDS
- Vol. 22 (5), 256-262
- https://doi.org/10.1258/ijsa.2009.009255
Abstract
This study examined pre-exposure prophylaxis (PrEP) acceptability among female sex workers, male-to-female transgendered persons and men who have sex with men in Lima, Peru. Focus groups explored social issues associated with PrEP acceptability and conjoint analysis assessed preferences among eight hypothetical PrEP scenarios with varying attribute profiles and their relative impact on acceptability. Conjoint analysis revealed that PrEP acceptability ranged from 19.8 to 82.5 out of a possible score of 100 across the eight hypothetical PrEP scenarios. Out-of-pocket cost had the greatest impact on PrEP acceptability (25.2, P < 0.001), followed by efficacy (21.4, P < 0.001) and potential side-effects (14.7, P < 0.001). Focus group data supported these findings, and also revealed that potential sexual risk disinhibition, stigma and discrimination associated with PrEP use, and mistrust of healthcare professionals were also concerns. These issues will require careful attention when planning for PrEP roll-out.Keywords
This publication has 38 references indexed in Scilit:
- Future HIV Vaccine Acceptability Among Young Adults in South AfricaHealth Education & Behavior, 2009
- HIV vaccine acceptability among immigrant Thai residents in Los Angeles: a mixed-method approachAIDS Care, 2008
- After the fall from grace: negotiation of new identities among HIV‐positive women in PeruCulture, Health & Sexuality, 2008
- The Impact of Pre-Exposure Prophylaxis (PrEP) on HIV Epidemics in Africa and India: A Simulation StudyPLOS ONE, 2008
- Knowledge and acceptability of alternative HIV prevention bio-medical products among MSM who barebackAIDS Care, 2008
- Potential Impact of Antiretroviral Chemoprophylaxis on HIV-1 Transmission in Resource-Limited SettingsPLOS ONE, 2007
- Willingness to participate in HIV vaccine trials: The impact of trial attributesPreventive Medicine, 2007
- Partner Notification for Sexually Transmitted Diseases in Peru: Knowledge, Attitudes, and Practices in a High-Risk CommunitySexually Transmitted Diseases, 2007
- Clients of Female Sex Workers in Lima, PeruSexually Transmitted Diseases, 2004
- Simultaneous conjoint measurement: A new type of fundamental measurementJournal of Mathematical Psychology, 1964