Takayasu’s arteritis and fibromuscular dysplasia as causes of acquired atypical coarctation of the aorta: retrospective analysis of seven cases
- 1 November 1999
- journal article
- research article
- Published by Springer Science and Business Media LLC in Heart and Vessels
- Vol. 14 (6), 277-282
- https://doi.org/10.1007/bf03257239
Abstract
Coarctation of the aorta usually occurs in the aortic isthmus; however, 2% of all coarctation is localized at atypical sites such as the aortic arch and the thoracic and/or abdominal aorta. Causal therapy involves vascular surgery, and during the procedure, biopsies of the involved vessels should be taken to establish the etiology. This study involved the retrospective analysis of clinical and histopathological findings for seven patients who underwent vascular surgical procedures (age range, 10–37 years; male/female ratio 3∶4). Histopathological analysis of specimens revealed two pathological processes taking place with different localization in the aortic wall as the cause of the atypical coarctation of the aorta: (1) fibrosis/scarification in the tunica media and adventitia compatible with chronic lesions of Takayasu’s arteritis (four cases); (2) fibromuscular dysplasia in the tunica media (three cases).Keywords
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