Comparison of minimally invasive closed circuit versus standard extracorporeal circulation for aortic valve replacement: a randomized study☆
Open Access
- 1 July 2009
- journal article
- research article
- Published by Oxford University Press (OUP) in Interactive CardioVascular and Thoracic Surgery
- Vol. 9 (1), 37-41
- https://doi.org/10.1510/icvts.2008.192559
Abstract
To evaluate the clinical results of aortic valve replacement performed with a miniaturized closed circuit extracorporeal circulation (MECC) system and to compare it to standard cardiopulmonary bypass (CPB). One hundred and twenty consecutive patients undergoing isolated aortic valve replacement were randomly assigned to either a miniaturized closed circuit CPB with the maquet-cardiopulmonary MECC System© (study group, n=60) or to a standard CPB (control group, n=60). Demographic characteristic and operative data were similar in the two groups. No hospital death occurred in either group and no difference in intensive care unit (ICU) stay and in-hospital stay was observed. Patients in the study group showed lower chest tube drainage (212±62 ml vs. 420±219 ml, PP9/l vs. 164±75×10 9/l, P=0.05). Peak postoperative troponin I release was significantly lower in the MECC group (3.81±2.7 ng/dl vs. 6.6±6.8 ng/dl, P<0.05). In this randomized study the MECC system has demonstrated best postoperative clinical results in terms of need for transfusion, platelets consumption and myocardial damage as compared to standard CPB.Keywords
This publication has 14 references indexed in Scilit:
- Effect of closed minimized cardiopulmonary bypass on cerebral tissue oxygenation and microembolizationThe Journal of Thoracic and Cardiovascular Surgery, 2006
- Minimal versus conventional cardiopulmonary bypass: assessment of intraoperative myocardial damage in coronary bypass surgeryEuropean Journal of Cardio-Thoracic Surgery, 2005
- Comparison of minimally invasive closed circuit extracorporeal circulation with conventional cardiopulmonary bypass and with off-pump technique in CABG patients: selected parameters of coagulation and inflammatory systemEuropean Journal of Cardio-Thoracic Surgery, 2005
- Aortic valve replacement with the minimal extracorporeal circulation (Jostra MECC System) versus standard cardiopulmonary bypass: A randomized prospective trialThe Journal of Thoracic and Cardiovascular Surgery, 2004
- Reduction of the inflammatory response following coronary bypass grafting with total minimal extracorporeal circulationEuropean Journal of Cardio-Thoracic Surgery, 2002
- Hemostatic Activation and Inflammatory Response during Cardiopulmonary BypassAnesthesiology, 2002
- Interleukin-1, interleukin-6 and myocardial enzyme response after coronary artery bypass grafting – a prospective randomized comparison of the conventional and three minimally invasive surgical techniques✩European Journal of Cardio-Thoracic Surgery, 2000
- Reducing the Post-Pump Syndrome by Using Heparin-Coated Circuits, Steroids, or AprotininThe Thoracic and Cardiovascular Surgeon, 1999
- Haemolysis during cardiopulmonary bypass: an in vivo comparison of standard roller pumps, nonocclusive roller pumps and centrifugal pumpsPerfusion, 1999
- Retransfusion of suctioned blood during cardiopulmonary bypass impairs hemostasisThe Annals of Thoracic Surgery, 1995