The chemistry of indoles. XXVII. A practical synthesis of the 1-methoxy analog of an ergot alkaloid, (.+-.)-1-methoxy-6,7-secoagroclavine.

Abstract

The first syntheses of 1-methoxy analogs of ergot alkaloids, (±)-1-methoxy-6, 7-secoagroclavine and (±)1-methoxy-6-nor-6, 7-secoagroclavine, were achieved with good overall yield in only nine steps from 2-nitrotoluene