Plasmodium-mosquito interactions: a tale of dangerous liaisons
- 6 September 2005
- journal article
- review article
- Published by Hindawi Limited in Cellular Microbiology
- Vol. 7 (11), 1539-1545
- https://doi.org/10.1111/j.1462-5822.2005.00615.x
Abstract
To complete their life cycle, Plasmodium parasites must survive the environment in the insect host, cross multiple barriers including epithelial layers, and avoid destruction by the mosquito immune system. Completion of the Anopheles gambiae and Plasmodium falciparum genomes has opened the opportunity to apply high throughput methods to the analysis of gene function. The burst of information generated by these approaches and the use of molecular markers to investigate the cell biology of these interactions is broadening our understanding of this complex system. This review discusses our current understanding of the critical interactions that take place during the journey of Plasmodium through the mosquito host, with special emphasis on the responses of midgut epithelial cells to parasite invasion.Keywords
This publication has 51 references indexed in Scilit:
- A chemotactic response facilitates mosquito salivary gland infection by malaria sporozoitesJournal Of Experimental Biology, 2005
- Mosquito immunity against PlasmodiumInsect Biochemistry and Molecular Biology, 2005
- Motility and infectivity of Plasmodium berghei sporozoites expressing avian Plasmodium gallinaceum circumsporozoite proteinCellular Microbiology, 2005
- Storage and secretion of Ag-Aper14, a novel peritrophic matrix protein, and Ag-Muc1 from the mosquito Anopheles gambiaeCell and tissue research, 2005
- How do malaria ookinetes cross the mosquito midgut wall?Trends in Parasitology, 2005
- PLASMODIUMSPOROZOITE MOLECULAR CELL BIOLOGYAnnual Review of Cell and Developmental Biology, 2004
- Overexpression and altered nucleocytoplasmic distribution of Anopheles ovalbumin-like SRPN10 serpins in Plasmodium-infected midgut cellsCellular Microbiology, 2004
- Monoclonal Antibody MG96 Completely Blocks Plasmodium yoelii Developmentin AnophelesstephensiInfection and Immunity, 2003
- Bee Venom Phospholipase Inhibits Malaria Parasite Development in Transgenic MosquitoesJournal of Biological Chemistry, 2002
- Disruption ofPlasmodium falciparumChitinase Markedly Impairs Parasite Invasion of Mosquito MidgutInfection and Immunity, 2001