Resting heart rate as a low tech predictor of coronary events in women: prospective cohort study

Abstract

OBJECTIVE: To evaluate resting heart rate as an independent predictor of cardiovascular risk in women.DESIGN: Prospective cohort study.SETTING: The Women's Health Initiative was undertaken at 40 research clinics in the United States.PARTICIPANTS: 129 135 postmenopausal women.MAIN OUTCOME MEASURE: Clinical cardiovascular events.RESULTS: During a mean of 7.8 (SD 1.6) years of follow up, 2281 women were identified with myocardial infarction or coronary death and 1877 with stroke. We evaluated associations between resting heart rate and cardiovascular events in Cox regression models adjusted for multiple covariates. Higher resting heart rate was independently associated with coronary events (hazard ratio 1.26, 95% confidence interval 1.11 to 1.42 for highest [>76 beats per minute] v lowest quintile [ PMID: 19193613 Funding information This work was supported by: WHI NIH HHS, United States Grant ID: N01WH44221 WHI NIH HHS, United States Grant ID: N01WH42132 WHI NIH HHS, United States Grant ID: N01WH42131 WHI NIH HHS, United States Grant ID: N01WH42130 WHI NIH HHS, United States Grant ID: N01WH42129 WHI NIH HHS, United States Grant ID: N01WH42126 WHI NIH HHS, United States Grant ID: N01WH42125 WHI NIH HHS, United States Grant ID: N01WH42124 WHI NIH HHS, United States Grant ID: N01WH42123 WHI NIH HHS, United States Grant ID: N01WH42122 WHI NIH HHS, United States Grant ID: N01WH42121 WHI NIH HHS, United States Grant ID: N01WH42120 WHI NIH HHS, United States Grant ID: N01WH42119 WHI NIH HHS, United States Grant ID: N01WH42118 WHI NIH HHS, United States Grant ID: N01WH42117 WHI NIH HHS, United States Grant ID: N01WH42116 WHI NIH HHS, United States Grant ID: N01WH42115 WHI NIH HHS, United States Grant ID: N01WH42114 WHI NIH HHS, United States Grant ID: N01WH42113 WHI NIH HHS, United States Grant ID: N01WH42112 WHI NIH HHS, United States Grant ID: N01WH42111 WHI NIH HHS, United States Grant ID: N01WH42110 WHI NIH HHS, United States Grant ID: N01WH42109 WHI NIH HHS, United States Grant ID: N01WH42108 WHI NIH HHS, United States Grant ID: N01WH42107 WHI NIH HHS, United States Grant ID: N01WH32122 WHI NIH HHS, United States Grant ID: N01WH32119 WHI NIH HHS, United States Grant ID: N01WH32118 WHI NIH HHS, United States Grant ID: N01WH32115 WHI NIH HHS, United States Grant ID: N01WH32113 WHI NIH HHS, United States Grant ID: N01WH32112 WHI NIH HHS, United States Grant ID: N01WH32111 WHI NIH HHS, United States Grant ID: N01WH32109 WHI NIH HHS, United States Grant ID: N01WH32108 WHI NIH HHS, United States Grant ID: N01WH32106 WHI NIH HHS, United States Grant ID: N01WH32105 WHI NIH HHS, United States Grant ID: N01WH32102 WHI NIH HHS, United States Grant ID: N01WH32101 WHI NIH HHS, United States Grant ID: N01WH32100 WHI NIH HHS, United States Grant ID: N01WH24152 WHI NIH HHS, United States Grant ID: N01WH22110 More Less keyboard_arrow_down