Electrophoretic Analysis of Serum Proteins in Infants and Children

Abstract

THE rapid accumulation of pediatric literature describing the occurrence in certain children of the recently recognized clinical entity, congenital agammaglobulinemia (hypogammaglobulinemia),^{1 2 3} has stimulated further research into the changes in the serum-protein fractions produced by other illnesses in patients in the pediatric age group. Before investigation of the alteration of serum-protein patterns in pathologic states in children can be performed, however, it is necessary to establish the normal range of values of the separate protein fractions in young infants and children. The data^{4 5 6 7 8 9 10} on this subject are sparse, and were compiled mainly in the era before filter-paper electrophoresis; in addition most . . .