Diffusion‐weighted magnetic resonance imaging in the differentiation of angiomyolipoma with minimal fat from clear cell renal cell carcinoma
- 4 August 2011
- journal article
- Published by Wiley in International Journal of Urology
- Vol. 18 (10), 727-730
- https://doi.org/10.1111/j.1442-2042.2011.02824.x
Abstract
The aim of the present study was to evaluate diffusion-weighted (DW) magnetic resonance imaging (MRI) in differentiating between minimal fat angiomyolipoma (MFAML) and clear cell renal cell carcinoma (CCRCC). Forty-one solid renal tumors without visible macroscopic fat on unenhanced computed tomography images were evaluated by MRI, including DW-MRI, and were diagnosed pathologically as CCRCC (n = 36) or MFAML (n = 5). To evaluate the heterogeneity of diffusion in each tumor, the signals of the tumors on DW-MRI were analyzed subjectively and the apparent diffusion coefficient (ADC) values and histograms assessed objectively. Thirty-three of 36 CCRCC (92%) exhibited a heterogeneous signal on DW-MRI and several peaks in the ADC value histogram, whereas four of five MFAML exhibited a homogeneous signal on DW-MRI and a single prominent peak in the histogram. The standard deviations of the ADC values were significantly smaller for MFAML than for CCRCC (P = 0.0015). In conclusion, DW-MRI can be considered a useful and noninvasive addition to the preoperative differentiation of CCRCC and MFAML.This publication has 9 references indexed in Scilit:
- Initial Experience of Diffusion-weighted Magnetic Resonance Imaging to Assess Therapeutic Response to Induction Chemoradiotherapy Against Muscle-invasive Bladder CancerUrology, 2009
- Diffusion-Weighted Magnetic Resonance Imaging as a Cancer Biomarker: Consensus and RecommendationsNeoplasia, 2009
- Renal Masses: Characterization with Diffusion-weighted MR Imaging—A Preliminary ExperienceRadiology, 2008
- Initial experience of functional imaging of upper urinary tract neoplasm by diffusion‐weighted magnetic resonance imagingInternational Journal of Urology, 2008
- Diffusion-Weighted MRI in the Body: Applications and Challenges in OncologyAmerican Journal of Roentgenology, 2007
- Angiomyolipoma with Minimal Fat: Differentiation from Renal Cell Carcinoma at Biphasic Helical CTRadiology, 2004
- Angiomyolipoma: imaging findings in lesions with minimal fat.Radiology, 1997
- Benign Renal Tumors Detected among Healthy Adults by Abdominal UltrasonographyEuropean Urology, 1995
- The Management of Renal AngiomyolipomaJournal of Urology, 1986