Miniaturization of Scorpion β-Toxins Uncovers a Putative Ancestral Surface of Interaction with Voltage-gated Sodium Channels
Open Access
- 30 May 2008
- journal article
- Published by Elsevier BV
- Vol. 283 (22), 15169-15176
- https://doi.org/10.1074/jbc.m801229200
Abstract
No abstract availableThis publication has 38 references indexed in Scilit:
- Design of a Specific Activator for Skeletal Muscle Sodium Channels Uncovers Channel ArchitecturePublished by Elsevier BV ,2007
- The differential preference of scorpion α-toxins for insect or mammalian sodium channels: Implications for improved insect controlToxicon, 2007
- The insecticidal potential of scorpion β-toxinsToxicon, 2007
- X-ray Structure and Mutagenesis of the Scorpion Depressant Toxin LqhIT2 Reveals Key Determinants Crucial for Activity and Anti-Insect SelectivityJournal of Molecular Biology, 2007
- Allosteric interactions between scorpion toxin receptor sites on voltage‐gated Na channels imply a novel role for weakly active components in arthropod venomThe FASEB Journal, 2006
- Structure and Function of the Voltage Sensor of Sodium Channels Probed by a β-Scorpion ToxinPublished by Elsevier BV ,2006
- Effect of Depolarization on Binding Kinetics of Scorpion α-Toxin Highlights Conformational Changes of Rat Brain Sodium ChannelsBiochemistry, 2001
- Solution structure of toxin 2 from Centruroides noxius Hoffmann, a β-scorpion neurotoxin acting on sodium channelsJournal of Molecular Biology, 1999
- Binding of an α scorpion toxin to insect sodium channels is not dependent on membrane potentialFEBS Letters, 1993
- Refined Structure of Charybdotoxin: Common Motifs in Scorpion Toxins and Insect DefensinsScience, 1991