Capsular Type and Antibiotic Resistance in Streptococcus agalactiae Isolates from Patients, Ranging from Newborns to the Elderly, with Invasive Infections
Open Access
- 1 June 2009
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 53 (6), 2650-2653
- https://doi.org/10.1128/aac.01716-08
Abstract
Streptococcus agalactiae isolates ( n = 189) from patients with invasive infections were analyzed for capsular type by PCR, for antimicrobial susceptibility, and for the presence of resistance genes. In contrast to the predominance of capsular type III in children, types Ib and V were most common among adults. All 45 levofloxacin-resistant strains had two amino acid substitutions, Ser 81 Leu in the gyrA gene and Ser 79 Phe in the parC gene, and showed similar pulsed-field gel electrophoresis patterns.Keywords
This publication has 24 references indexed in Scilit:
- Distribution of emm type and antibiotic susceptibility of group A streptococci causing invasive and noninvasive diseaseJournal of Medical Microbiology, 2008
- First Molecular Characterization of Group B Streptococci with Reduced Penicillin SusceptibilityAntimicrobial Agents and Chemotherapy, 2008
- Multiplex PCR Assay for Rapid and Accurate Capsular Typing of Group B StreptococciJournal of Clinical Microbiology, 2007
- Fluoroquinolone-Resistant Streptococcus agalactiae : Epidemiology and Mechanism of ResistanceAntimicrobial Agents and Chemotherapy, 2005
- First Streptococcus agalactiae Isolates Highly Resistant to Quinolones, with Point Mutations in gyrA and parCAntimicrobial Agents and Chemotherapy, 2003
- Early-Onset Group B Streptococcal Disease--United States, 1998-1999Published by American Medical Association (AMA) ,2000
- Prevention of early‐onset group B streptococcal disease in newbornsInternational Journal of Gynecology & Obstetrics, 1996
- Suppurative meningitis due to streptococci of lancefield group B: A study of 33 infantsThe Journal of Pediatrics, 1973
- Group B beta hemolytic streptococcal meningitis in infantsThe Journal of Pediatrics, 1973
- Group B streptococcal neonatal and infant infectionsThe Journal of Pediatrics, 1973