Radical ablative surgery and radial forearm free flap (RFFF) reconstruction for patients with oral or oropharyngeal cancer: postoperative outcomes and oncologic and functional results
- 1 January 2009
- journal article
- research article
- Published by Taylor & Francis Ltd in Acta Oto-Laryngologica
- Vol. 129 (6), 681-687
- https://doi.org/10.1080/00016480802369260
Abstract
Conclusions. Radical ablative surgery and radial forearm free flap (RFFF) reconstruction provide promising oncologic and functional results in patients with oral or oropharyngeal cancer. Objectives. To assess the postoperative outcomes and the oncologic and functional results, with their main predictive factors, after radical ablative surgery and RFFF reconstruction for patients with oral or oropharyngeal cancer. Patients and methods. Between 2000 and 2006, we prospectively analyzed the postoperative, oncologic and functional outcomes of all previously untreated patients who underwent this type of surgery. Results. A total of 132 patients were enrolled in this study. There were three RFFF failures. The rate of surgical complications was 20%. The 5-year locoregional control and overall survival rates were 68% and 52%, respectively. Advanced age, high comorbidity index, elevated overall stage and tumoral involvement of the inner part of the cheek were correlated with a lower overall survival rate. A good functional result was obtained for oral diet, speech, mouth opening and aesthetic outcome in 87%, 80%, 86% and 88% of the patients, respectively. High comorbidity index, large flap surface, radiotherapy and tumoral involvement of the mobile tongue were significant predictors of poorer functional or aesthetic outcomes.Keywords
This publication has 19 references indexed in Scilit:
- Head and neck reconstruction with free flaps: a report on 213 casesEuropean Archives of Oto-Rhino-Laryngology, 2007
- Functional outcomes after surgical reconstruction of the base of tongue using the radial forearm free flap in patients with oropharyngeal carcinomaHead & Neck, 2007
- Squamous cell carcinoma of the buccal mucosa: An aggressive cancer requiring multimodality treatmentHead & Neck, 2005
- Surgery and adjuvant radiotherapy vs concurrent chemoradiotherapy in stage III/IV nonmetastatic squamous cell head and neck cancer: a randomised comparisonBritish Journal of Cancer, 2005
- Analysis of Outcome and Complications in 400 Cases of Microvascular Head and Neck ReconstructionJAMA Otolaryngology–Head & Neck Surgery, 2004
- Advances in Head and Neck ReconstructionThe Laryngoscope, 2003
- Microvascular free tissue transfer in elderly patients: The Toronto experienceHead & Neck, 2003
- Simplifying Microvascular Head and Neck ReconstructionAnnals of Plastic Surgery, 2001
- Free Flap Reconstruction of the Head and Neck: Analysis of 241 CasesOtolaryngology -- Head and Neck Surgery, 2001
- The importance of classifying initial co-morbidity in evaluating the outcome of diabetes mellitusJournal of Chronic Diseases, 1974