Papain-Assisted Resolution of Natural and Xenobiotic α-Amino Acid
- 1 April 1988
- journal article
- research article
- Published by Taylor & Francis Ltd in Synthetic Communications
- Vol. 18 (4), 441-444
- https://doi.org/10.1080/00397918808064007
Abstract
A new and convenient method for the preparation of pure enantiomers of α-amino acids is described. Industrial papain, catalyzes the synthesis of L-Z-amino acid ethyl esters in ethanolic medium, with good yields. These esters are obtained from DL-Z-amino acids with 100% optical purity. Unreactive D-Z-amino acids are readily isolated from reaction medium. Physical constants of natural and xenobiotic L-Z-amino acid esters and D-Z-amino acids are described.Keywords
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