Relationship between obsessive-compulsive disorders and diseases affecting primarily the basal ganglia
Open Access
- 1 December 1999
- journal article
- review article
- Published by FapUNIFESP (SciELO) in Revista Do Hospital Das Clinicas
- Vol. 54 (6), 213-221
- https://doi.org/10.1590/s0041-87811999000600008
Abstract
Obsessive-compulsive disorder (OCD) has been reported in association with some neurological diseases that affect the basal ganglia such as Tourette's syndrome, Sydenham's chorea, Parkinson's disease, and Huntington's disease. Furthermore, studies such as neuroimaging, suggest a role of the basal ganglia in the pathophysiology of OCD. The aim of this paper is to describe the association of OCD and several neurologic disorders affecting the basal ganglia, report the existing evidences of the role of the basal ganglia in the pathophysiology of OCD, and analyze the mechanisms probably involved in this pathophysiology.Keywords
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