Dexmedetomidine: perioperative applications in children
- 17 February 2010
- journal article
- Published by Wiley in Pediatric Anesthesia
- Vol. 20 (3), 256-264
- https://doi.org/10.1111/j.1460-9592.2009.03207.x
Abstract
Dexmedetomidine is a highly specific and selective alpha-2-adrenergic agonist with sedative, anxiolytic, and organ protective effects. Its clinical applications in children include premedication, prevention of emergence delirium, as part of multimodal anesthetic regimen and sedation in the pediatric intensive care unit. Its role in neuroprotection in children undergoing anesthesia should be explored. In this review, various uses of dexmedetomidine are discussed in detail.Keywords
This publication has 79 references indexed in Scilit:
- Effects of variation in the human α2A‐ and α2C‐adrenoceptor genes on cognitive tasks and pain perceptionEuropean journal of pain, 2010
- Early Exposure to Anesthesia and Learning Disabilities in a Population-based Birth CohortAnesthesiology, 2009
- Effect of dexmedetomidine on the characteristics of bupivacaine in a caudal block in pediatricsActa Anaesthesiologica Scandinavica, 2009
- Effects of dexmedetomidine on propofol and remifentanil infusion rates during total intravenous anesthesia for spine surgery in adolescentsPediatric Anesthesia, 2008
- Electroencephalogram spindle activity during dexmedetomidine sedation and physiological sleepActa Anaesthesiologica Scandinavica, 2007
- Fentanyl or dexmedetomidine combined with desflurane for bariatric surgeryJournal of Clinical Anesthesia, 2006
- Dexmedetomidine during local anesthesiaJournal of Anesthesia, 2006
- The effect of pre-anaesthetic administration of intravenous dexmedetomidine on postoperative pain in patients receiving patient-controlled morphineEuropean Journal of Anaesthesiology, 2005
- Bioavailability of dexmedetomidine after extravascular doses in healthy subjectsBritish Journal of Clinical Pharmacology, 2003
- Preoperative preparation in children: A cross-sectional studyJournal of Clinical Anesthesia, 1996