Disseminated aspergillosis in two dogs in Israel
- 8 February 2006
- Vol. 49 (2), 130-133
- https://doi.org/10.1111/j.1439-0507.2006.01168.x
Abstract
Aspergillus terreus, normally a soil or plant saprophyte, causes disseminated systemic infection, involving primarily the skeletal and the cardiopulmonary system in humans and dogs.(1, 2) We describe two cases of German shepherd dogs that were referred to Koret School of Veterinary Medicine Teaching Hospital with a history of anorexia and weakness. Case 1 suffered from neurological deficits, paraparesis and lumbar pain whereas case 2 suffered from unilateral uveitis and exophthalmus. Both dogs were treated symptomatically, but deteriorated progressively despite therapy and were therefore euthanised. Necropsy revealed disseminated aspergillosis, and numerous organs had multiple, miliary, white-yellow foci. Microscopically, these were identified as granulomas, containing fungal hyphae. Affected tissue included brain, heart, kidneys, spleen, lymph nodes and bones (case 2). Aspergillus terreus was isolated from different organs and from urine culture. We suggest that disseminated aspergillosis should be considered as a differential diagnosis in German shepherd dogs presenting with ocular disease, neurological deficits, spinal column pain, urinary system disorders, and radiographic evidence of skeletal and/or respiratory pathology.Keywords
This publication has 4 references indexed in Scilit:
- Long‐term survival of four dogs with disseminated Aspergillus terreus infection treated with itraconazoleAustralian Veterinary Journal, 1995
- Disseminated aspergillosis in dogsAustralian Veterinary Journal, 1986
- The Pathology of Disseminated Aspergillus terreus Infection in DogsVeterinary Pathology, 1985
- Aspergillus fumigatus infection in the nasal cavity of a dog: its treatment with amphotericin BPublished by Wiley ,1973