Incidence of Late-Onset Bleb-Related Complications Following Trabeculectomy With Mitomycin

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Abstract
TRABECULECTOMY remains the standard of care for patients who have failed maximal tolerated medical therapy. Risk factors, such as previous surgery, age, and race, may predispose patients to bleb failure if an antifibrotic agent is not used with trabeculectomy. The use of intraoperative mitomycin as an adjunct to standard trabeculectomy has increased the likelihood that this procedure will maintain low intraocular pressures.1 Because of this greater chance of long-term intraocular pressure control, mitomycin is used frequently in high-risk cases.