Constitutive Receptor Activity series Endogenous inverse agonists and constitutive receptor activity in the melanocortin system
- 30 April 2006
- journal article
- review article
- Published by Elsevier BV in Trends in Pharmacological Sciences
- Vol. 27 (4), 183-186
- https://doi.org/10.1016/j.tips.2006.02.002
Abstract
No abstract availableKeywords
This publication has 14 references indexed in Scilit:
- New Concepts in Drug Discovery: Collateral Efficacy and Permissive AntagonismNature Reviews Drug Discovery, 2005
- Obesity-associated mutations in the melanocortin 4 receptor provide novel insights into its functionPeptides, 2005
- Hypothalamic neuropeptide expression following chronic food restriction in sedentary and wheel-running ratsJournal of Molecular Endocrinology, 2005
- Preservation of Eumelanin Hair Pigmentation in Proopiomelanocortin-Deficient Mice on a Nonagouti (a/a) Genetic BackgroundEndocrinology, 2005
- Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humansJCI Insight, 2004
- Inverse agonism gains weightTrends in Pharmacological Sciences, 2003
- Constitutive Desensitization: A New Paradigm for G Protein-Coupled Receptor RegulationASSAY and Drug Development Technologies, 2003
- High constitutive activity of native H3 receptors regulates histamine neurons in brainNature, 2000
- Inverse agonism at heptahelical receptors: concept, experimental approach and therapeutic potentialFundamental & Clinical Pharmacology, 2000
- Photoperiod regulates arcuate nucleus POMC, AGRP, and leptin receptor mRNA in Siberian hamster hypothalamus.American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2000