In-Home Coal and Wood Use and Lung Cancer Risk: A Pooled Analysis of the International Lung Cancer Consortium
- 30 November 2010
- journal article
- research article
- Published by Environmental Health Perspectives in Environmental Health Perspectives
- Vol. 118 (12), 1743-1747
- https://doi.org/10.1289/ehp.1002217
Abstract
BACKGROUND: Domestic fuel combustion from cooking and heating is an important public health issue because roughly 3 billion people are exposed worldwide. Recently, the International Agency for Research on Cancer classified indoor emissions from household coal combustion as a human carcinogen (group 1) and from biomass fuel (primarily wood) as a probable human carcinogen (group 2A). OBJECTIVES: We pooled seven studies from the International Lung Cancer Consortium (5,105 cases and 6,535 controls) to provide further epidemiological evaluation of the association between in-home solid-fuel use, particularly wood, and lung cancer risk. METHODS: Using questionnaire data, we classified subjects as predominant solid-fuel users (e. g., coal, wood) or nonsolid-fuel users (e.g., oil, gas, electricity). Unconditional logistic regression was used to estimate the odds ratios (ORs) and to compute 95% confidence intervals (CIs), adjusting for age, sex, education, smoking status, race/ethnicity, and study center. RESULTS: Compared with nonsolid-fuel users, predominant coal users (OR = 1.64; 95% CI, 1.49-1.81), particularly coal users in Asia (OR = 4.93; 95% CI, 3.73-6.52), and predominant wood users in North American and European countries (OR = 1.21; 95% CI, 1.06-1.38) experienced higher risk of lung cancer. The results were similar in never-smoking women and other subgroups. CONCLUSIONS: Our results are consistent with previous observations pertaining to in-home coal use and lung cancer risk, support the hypothesis of a carcinogenic potential of in-home wood use, and point to the need for more detailed study of factors affecting these associations.Keywords
This publication has 43 references indexed in Scilit:
- Lung Cancer in a U.S. Population with Low to Moderate Arsenic ExposureEnvironmental Health Perspectives, 2009
- Dietary Intake of Methionine, Cysteine, and Protein and Urinary Arsenic Excretion in BangladeshEnvironmental Health Perspectives, 2009
- Portable stove use is associated with lower lung cancer mortality risk in lifetime smoky coal usersBritish Journal of Cancer, 2008
- Indoor air pollution from solid fuel use, chronic lung diseases and lung cancer in Harbin, Northeast ChinaEuropean Journal of Cancer Prevention, 2008
- Variation in lung cancer risk by smoky coal subtype in Xuanwei, ChinaInternational Journal of Cancer, 2008
- A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25Nature, 2008
- GST genotypes and lung cancer susceptibility in Asian populations with indoor air pollution exposures: A meta-analysisMutation Research - Reviews in Mutation Research, 2007
- GSTM1andCYP1A1Polymorphisms, Tobacco, Air Pollution, and Lung Cancer: A Study in Rural ThailandCancer Epidemiology, Biomarkers & Prevention, 2006
- Case–control study of indoor cooking smoke exposure and cataract in Nepal and IndiaInternational Journal of Epidemiology, 2005
- Smoking, Air Pollution, and the High Rates of Lung Cancer in Shenyang, ChinaJNCI Journal of the National Cancer Institute, 1989