Prevalence and Correlates of Sleep‐Disordered Breathing in Older Men: Osteoporotic Fractures in Men Sleep Study
- 2 July 2007
- journal article
- research article
- Published by Wiley in Journal of the American Geriatrics Society
- Vol. 55 (9), 1356-1364
- https://doi.org/10.1111/j.1532-5415.2007.01290.x
Abstract
To determine the prevalence and distribution of sleep-disordered breathing and associated correlates in a large cohort of older men using several standardized definitions. Cross-sectional analyses. Six U.S. communities. Polysomnography was performed on 2,911 participants of the Outcomes of Sleep Disorders in Older Men Sleep Study (mean age+/-standard deviation 76.38+/-5.53; body mass index 27.17+/-3.8 kg/m(2)). Three outcomes were assessed: sleep-disordered breathing (respiratory disturbance index > or =15), obstructive apnea (obstructive apnea index > or =5), and central apnea (central apnea index > or =5). The prevalence of moderate-severe sleep-disordered breathing was estimated to be 21.4% to 26.4%. Multivariable logistic regression models demonstrated that age (adjusted odds ratio (AOR) per 5-year increase =1.24, 95% confidence interval (CI)=1.15-1.34), obesity (AOR=2.54, 95% CI=2.09-3.09), Asian versus Caucasian race (AOR=2.14, 95% CI=1.33-3.45), snoring (AOR=2.01, 95% CI=1.62-2.49), sleepiness (AOR=1.41, 95% CI=1.11-1.79), hypertension (AOR=1.26, 95% CI=1.06-1.50), cardiovascular disease (AOR=1.24, 95% CI=1.19-1.29), and heart failure (AOR=1.81, 1.31-2.51) were independently associated with sleep-disordered breathing; snoring (AOR=2.10, 95% CI=1.67-2.70), age (AOR per 5-year increase=1.27, 95% CI=1.18-1.38), obesity (AOR=1.48, 95% CI=1.21-1.82), and heart failure (AOR=1.60, 95% CI=1.15-2.24) were associated with obstructive apnea; and age (AOR=1.33, 1.17-1.50) and heart failure (AOR=1.88, 95% CI=1.17-3.04) were associated with central apnea. Regardless of definition, a high prevalence of sleep disorders is observed in community-dwelling older men. Qualitatively similar associations were observed between sleep disorders and snoring, obesity, and comorbidities, as reported for middle aged populations. Asian race was associated with sleep-disordered breathing.This publication has 40 references indexed in Scilit:
- Frailty in Older AdultsPublished by Elsevier BV ,2006
- Design and baseline characteristics of the osteoporotic fractures in men (MrOS) study — A large observational study of the determinants of fracture in older menContemporary Clinical Trials, 2005
- Overview of recruitment for the osteoporotic fractures in men study (MrOS)Contemporary Clinical Trials, 2005
- Age-Dependent Associations Between Sleep-Disordered Breathing and HypertensionCirculation, 2005
- Prevalence of Sleep-disordered Breathing in Middle-aged Korean Men and WomenAmerican Journal of Respiratory and Critical Care Medicine, 2004
- Frailty in the elderly: contributions of sarcopenia and visceral protein depletionMetabolism, 2003
- Relationship of subjective and objective social status with psychological and physiological functioning: Preliminary data in healthy, White women.Health Psychology, 2000
- Sleep-disordered breathing in African-American elderly.American Journal of Respiratory and Critical Care Medicine, 1995
- The Occurrence of Sleep-Disordered Breathing among Middle-Aged AdultsThe New England Journal of Medicine, 1993
- Prevalence of Sleep Apnea among Japanese Industrial Workers Determined by a Portable Sleep Monitoring SystemRespiration, 1993