Effect of chemical modifications of cytosine and guanine in a cpg-motif of oligonucleotides: structure–immunostimulatory activity relationships
- 31 March 2001
- journal article
- Published by Elsevier BV in Bioorganic & Medicinal Chemistry
- Vol. 9 (3), 807-813
- https://doi.org/10.1016/s0968-0896(00)00316-3
Abstract
No abstract availableKeywords
This publication has 16 references indexed in Scilit:
- CpG Oligodeoxynucleotides and Interleukin-12 Improve the Efficacy ofMycobacterium bovisBCG Vaccination in Mice Challenged withM. tuberculosisInfection and Immunity, 2000
- Antisense therapeutics: is it as simple as complementary base recognition?Molecular Medicine Today, 2000
- Mechanisms and therapeutic applications of immune stimulatory CpG DNAPharmacology & Therapeutics, 1999
- Immunostimulatory DNA: Sequence‐dependent production of potentially harmful or useful cytokinesEuropean Journal of Immunology, 1997
- Pattern and Kinetics of Cytokine Production Following Administration of Phosphorothioate Oligonucleotides in MiceAntisense and Nucleic Acid Drug Development, 1997
- Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor‐α‐mediated shockEuropean Journal of Immunology, 1997
- CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma.Proceedings of the National Academy of Sciences of the United States of America, 1996
- Effect of different chemically modified oligodeoxynucleotides on immune stimulationBiochemical Pharmacology, 1996
- CpG motifs in bacterial DNA trigger direct B-cell activationNature, 1995
- Lipofection of Synthetic Oligodeoxyribonucleotide Having a Palindromic Sequence of AACGTT to Murine Splenocytes Enhances Interferon Production and Natural Killer ActivityMicrobiology and Immunology, 1994