Whole-Body Cryostimulation - Potential Beneficial Treatment for Improving Antioxidant Capacity in Healthy Men - Significance of the Number of Sessions
Open Access
- 15 October 2012
- journal article
- research article
- Published by Public Library of Science (PLoS) in PLOS ONE
- Vol. 7 (10), e46352
- https://doi.org/10.1371/journal.pone.0046352
Abstract
It is claimed that WBC (whole-body cryotherapy) enhances the resistance of the human body, also thanks to the beneficial effect on the antioxidant system. Accordingly, this research aimed to evaluate the effect of a series of whole-body cryostimulations on the level of non-enzymatic antioxidants and the activity of antioxidant enzymes in healthy men. The study was carried out on 30 young and healthy men aged 27.8±6.1 years with average body mass index and peak oxygen consumption (46.34±6.15 ml kg−1 •min−1). The participants were daily exposed for 3 minutes to cryogenic temperatures (−130°C). Blood samples were obtained in the morning before cryostimulation, again 30 min after exposure and the following day in the morning, during the 1st, 10th and 20th session. Analysis concerned changes in plasma concentrations of total protein, albumin, glucose, uric acid and ceruloplasmin, and the most important components of the antioxidant system in red blood cells: superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, reduced and oxidized glutathione. To assess the oxidative stress level the 8-isoprostane concentration in plasma was measured. The obtained results indicate that cryogenic temperatures in repeated daily treatments result in changes in the peroxidant and antioxidant status. These changes seem to depend on the number of cryostimulations. After 20 daily treatments there was an increase in SOD, SOD:CAT ratio, a decrease in the concentration of reduced and oxidized glutathione and in the activity of GPx. It could be possible that differences in the activity of GSSG-R after 20 treatments depended on the body mass index of participants.Keywords
This publication has 44 references indexed in Scilit:
- Effect of short-term cryostimulation on antioxidative status and its clinical applications in humansEuropean Journal of Applied Physiology, 2011
- The effects of whole-body cryotherapy on oxidative stress in multiple sclerosis patientsJournal of Thermal Biology, 2010
- Changes in blood pressure with compensatory heart rate decrease and in the level of aerobic capacity in response to repeated whole-body cryostimulation in normotensive, young and physically active menInternational Journal of Occupational Medicine and Environmental Health, 2010
- Effects of whole-body cryotherapy on serum mediators of inflammation and serum muscle enzymes in athletesJournal of Thermal Biology, 2009
- Hypothermia-enhanced splenic cytokine gene expression is independent of the sympathetic nervous systemAmerican Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 2006
- The isoprostane 8‐iso‐PGF 2α suppresses monocyte adhesion to human microvascular endothelial cells via two independent mechanismsThe FASEB Journal, 2004
- Cold-Induced VasoconstrictionCirculation Research, 2004
- Antioxidative defense in the rat skin after the adaptation to coldJournal of Thermal Biology, 2003
- Relation Between Serum Albumin and Carotid AtherosclerosisStroke, 2003
- Formation of PGF2-Isoprostanes During the Oxidative Modification of Low Density LipoproteinBiochemical and Biophysical Research Communications, 1994