Influence of the Extent of Resection on Survival After Curative Treatment of Gastric Carcinoma
- 1 November 1987
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Surgery
- Vol. 122 (11), 1347-1351
- https://doi.org/10.1001/archsurg.1987.01400230135024
Abstract
• The therapeutic value of extensive gastric resection and regional lymphadenectomy in the curative treatment of gastric adenocarcinoma is controversial. We undertook a retrospective study of 210 patients treated with curative intent from 1960 to 1980. A multivariate survival analysis using the Cox model revealed five significant variables predictive of death from gastric cancer—two inherent pathologic factors: (1) nonpyloric site and (2) metastases in more than three lymph nodes, and three treatment factors that could often be controlled by the surgeon: (3) microscopic positive gastric resection margin, (4) inadequate lymphadenectomy, and (5) total gastrectomy. These observations reaffirm the value of wide gastric resection and adequate lymphadenectomy but argue against a general policy ofelectivetotal gastrectomy in the curative treatment of gastric carcinoma. (Arch Surg1987;122:1347-1351)Keywords
This publication has 1 reference indexed in Scilit:
- The general rules for the gastric cancer study in surgery and pathologySurgery Today, 1981