Time-Resolved Reflectance at Null Source-Detector Separation: Improving Contrast and Resolution in Diffuse Optical Imaging
- 8 August 2005
- journal article
- research article
- Published by American Physical Society (APS) in Physical Review Letters
- Vol. 95 (7), 078101
- https://doi.org/10.1103/physrevlett.95.078101
Abstract
We propose a novel approach to imaging in diffusive media based on time-resolved reflectance measurements at null source-detector separation. This approach yields better spatial resolution and contrast as compared to the classical approach, which typically employs a separation of 20–40 mm. Results are obtained by an analytical perturbation approach to diffusion theory and on Monte Carlo simulations. Practical implementation with state-of-the-art technology and performance of a complementary approach based on the use of small but not null source-detector separation are also discussed.Keywords
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