Catalytic coupling of nitriles with amines to selectively form imines under mild hydrogen pressure
- 2 November 2012
- journal article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- Vol. 48 (97), 11853-11855
- https://doi.org/10.1039/c2cc36639h
Abstract
Imines are selectively formed by coupling of nitriles and amines under mild hydrogen pressure. The reaction is catalyzed by a bipyridine-based PNN Ru(II) pincer complex and proceeds under mild, neutral conditions at 4 bar of H2.Keywords
This publication has 45 references indexed in Scilit:
- Chemoselective Hydrogenation of α,β‐Unsaturated NitrilesAdvanced Synthesis & Catalysis, 2004
- Selective Hydrogenation for Fine Chemicals: Recent Trends and New DevelopmentsAdvanced Synthesis & Catalysis, 2003
- The Reductive Amination of Aldehydes and Ketones and the Hydrogenation of Nitriles: Mechanistic Aspects and Selectivity ControlAdvanced Synthesis & Catalysis, 2002
- Ruthenium Complexes Containing Bis(diarylamido)/Thioether Ligands: Synthesis and Their Catalysis for the Hydrogenation of BenzonitrileOrganometallics, 2002
- Versatile Reactivity of the Bis(dihydrogen) Complex RuH2(H2)2(PCy3)2 toward Functionalized Olefins: Olefin Coordination versus Hydrogen Transfer via the Stepwise Dehydrogenation of the Phosphine LigandOrganometallics, 1996
- Hydrogenation reactions with RuCl2(TRIPHOS)Journal of Molecular Catalysis, 1988
- Monomeric and dimeric ruthenium(II) .eta.2-dihydrogen complexes with tricyclohexylphosphine co-ligandsInorganic Chemistry, 1988
- Anionic metal hydride catalysts. 2. Application to the hydrogenation of ketones, aldehydes, carboxylic acid esters, and nitrilesJournal of the American Chemical Society, 1981
- Catalytic Hydrogenation of ButyronitrileI&EC Product Research and Development, 1967
- Über neue und über verbesserte Wege zum Aufbau von pharmakologisch wichtigen Aminen. VII. Über die Synthese von sekundären und tertiären Aminen durch Hydrierung von NitrilenArchiv der Pharmazie, 1933