Imaging Endolymphatic Hydrops at 3 Tesla Using 3D-FLAIR with Intratympanic Gd-DTPA Administration
- 1 January 2008
- journal article
- research article
- Published by Japanese Society for Magnetic Resonance in Medicine in Magnetic Resonance in Medical Sciences
- Vol. 7 (2), 85-91
- https://doi.org/10.2463/mrms.7.85
Abstract
Purpose: Visualization of endolymphatic hydrops by 3-dimensional fluid-attenuated inversion recovery-FLAIR using conventional turbo-spin-echo (3D-FLAIR-CONV) after intratympanic injection of Gd-DTPA has been reported in patients with Ménière's disease. Compared to 3D-FLAIR-CONV used in previous studies, the addition of a variable flip-angle technique (3D-FLAIR-VFL) enables very long echo trains and, therefore, shorter scan times. We evaluated whether 3D-FLAIR-VFL could replace 3D-FLAIR-CONV in detecting endolymphatic hydrops after intratympanic Gd-DTPA administration. Methods: Eleven patients were included in this study. Twenty-four hours after Gd-DTPA injection, we performed 3D-FLAIR-CONV and 3D-FLAIR-VFL imaging at 3T. We compared the contrast-to-noise ratio (CNR) between cochlear fluid and the cerebellum between the 2 FLAIR sequences. We subjectively scored the size of the endolymphatic space in the cochlea and vestibule for each patient and correlated the scores with the clinical diagnoses. Results: The CNR of 3D-FLAIR-CONV was significantly higher than that of 3D-FLAIR-VFL. Scores for the size of endolymphatic space in the vestibule were identical between the 2 sequences; however, those in the cochlea disagreed in 3 cases. 3D-FLAIR-CONV correlated better with the clinical diagnoses. Conclusions: Currently, we may not be able to replace 3D-FLAIR-CONV with 3D-FLAIR-VFL, at least not with the scanning parameters used in the present study.Keywords
This publication has 20 references indexed in Scilit:
- Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging findings in a patient with cochlear otosclerosisAuris Nasus Larynx, 2008
- Three-Dimensional Fluid-Attenuated Inversion Recovery Magnetic Resonance Imaging Investigation of Inner Ear Disturbances in Cases of Middle Ear Cholesteatoma With Labyrinthine FistulaOtology & Neurotology, 2007
- Visualization of Endolymphatic Hydrops in Patients With Meniere's DiseaseThe Laryngoscope, 2007
- 3D-FLAIR MRI findings in a patient with Ramsay Hunt syndromeActa Oto-Laryngologica, 2007
- 3D-FLAIR magnetic resonance imaging in the evaluation of mumps deafnessInternational Journal of Pediatric Otorhinolaryngology, 2006
- Visualization of a high protein concentration in the cochlea of a patient with a large endolymphatic duct and sac, using three-dimensional fluid-attenuated inversion recovery magnetic resonance imagingThe Journal of Laryngology & Otology, 2006
- Three‐Dimensional Fluid‐Attenuated Inversion Recovery Magnetic Resonance Imaging Findings in Patients with Sudden Sensorineural Hearing LossThe Laryngoscope, 2006
- Inner Ear Hemorrhage in Systemic Lupus ErythematosusThe Laryngoscope, 2006
- Prompt Contrast Enhancement of Cerebrospinal Fluid Space in the Fundus of the Internal Auditory Canal: Observations in Patients with Meningeal Diseases on 3D-FLAIR Images at 3 TeslaMagnetic Resonance in Medical Sciences, 2006
- Observation of contrast enhancement in the cochlear fluid space of healthy subjects using a 3D-FLAIR sequence at 3 TeslaEuropean Radiology, 2005