Protease‐Directed Drug Discovery
- 11 July 2008
- book chapter
- other
- Published by Wiley
Abstract
No abstract availableThis publication has 80 references indexed in Scilit:
- Structural Details on the Binding of Antihypertensive Drugs Captopril and Enalaprilat to Human Testicular Angiotensin I-Converting Enzyme,Biochemistry, 2004
- The Nonchiral Bislactim Diethoxy Ether as a Highly Stereo-Inducing Synthon for Sterically Hindered,γ-Branchedα-Amino Acids: A Practical, Large-Scale Route to an Intermediate of the Novel Renin Inhibitor AliskirenHelvetica Chimica Acta, 2003
- Crystal Structure of Human MMP9 in Complex with a Reverse Hydroxamate InhibitorJournal of Molecular Biology, 2002
- Analysis of crystal structures of aspartic proteinases: On the role of amino acid residues adjacent to the catalytic site of pepsin‐like enzymesProtein Science, 2001
- Solution structure of the catalytic domain of human collagenase-3 (MMP-13) complexed to a potent non-peptidic sulfonamide inhibitor: binding comparison with stromelysin-1 and collagenase-1Journal of Molecular Biology, 2000
- The metzincins — Topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a super family of zinc‐peptidasesProtein Science, 1995
- Ro 42-5892 is a potent orally active renin inhibitor in primates.Hypertension, 1991
- Mechanism of proline-specific proteinases: (I) substrate specificity of dipeptidyl peptidase IV from pig kidney and proline-specific endopeptidase from Flavobacterium meningosepticumBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1988
- Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive AgentsScience, 1977
- On the size of the active site in proteases. I. PapainBiochemical and Biophysical Research Communications, 1967