Immediate and mid-term outcomes of sirolimus-eluting stent implantation for chronic total occlusions
Open Access
- 7 April 2005
- journal article
- research article
- Published by Oxford University Press (OUP) in European Heart Journal
- Vol. 26 (11), 1056-1062
- https://doi.org/10.1093/eurheartj/ehi191
Abstract
Aims To evaluate the outcomes of sirolimus-eluting stent (SES) implantation for the treatment of chronic total occlusion (CTO). Methods and results We identified 122 patients who underwent revascularization in CTO lesions with SES from April 2002 to April 2004 (SES group). A control group was composed of 259 consecutive patients with CTO lesions treated with bare metal stents (BMS) in the 24 months immediately before the introduction of SES (BMS group). At 6-month follow-up, the cumulative rate of major adverse cardiac events (MACE) was 16.4% in the SES group and 35.1% in the BMS group (PPPPP20 mm) (HR: 2.02; 95% CI: 1.37–2.99; P=0.0004), and baseline reference vessel diameter (>2.8 mm) (HR: 0.62; 95% CI: 0.42–0.92; P=0.02) were identified as predictors of MACE during 6-month follow-up. Conclusion Compared with BMS, SES implantation in CTO lesions appears to be effective in reducing the incidence of restenosis and the need for revascularization at 6 months.Keywords
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