A sensitive assay of metoprolol and its major metabolite α-hydroxy metoprolol in human plasma and determination of dextromethorphan and its metabolite dextrorphan in urine with high performance liquid chromatography and fluorometric detection
- 28 February 1998
- journal article
- Published by Elsevier BV in Journal of Pharmaceutical and Biomedical Analysis
- Vol. 16 (6), 1041-1049
- https://doi.org/10.1016/s0731-7085(97)00115-5
Abstract
No abstract availableKeywords
This publication has 21 references indexed in Scilit:
- Individual Variation in First-Pass MetabolismClinical Pharmacokinetics, 1993
- Screening of β-blockers in human serum by ion-pair chromatography and their identification as methyl or acetyl derivatives by gas chromatography—mass spectrometryJournal of Chromatography A, 1993
- Simultaneous determination of propranolol or metoprolol in the presence of butyrophenones in human plasma by gas chromatography with mass spectrometryJournal of Pharmaceutical Sciences, 1993
- Use of 4-(N,N-dimethylaminosulphonyl)-7-fluoro-2,1,3-benzoxadiazole as a labelling reagent for peroxyoxalate chemiluminescence detection and its application to the determination of the β-blocker metoprolol in serum by high-performance liquid chromatographyThe Analyst, 1991
- Recent Developments in Hepatic Drug OxidationClinical Pharmacokinetics, 1990
- A strategy for the determination of beta blockers in plasma using solid-phase extraction in combination with high-performance liquid chromatographyJournal of Pharmaceutical and Biomedical Analysis, 1989
- Determination of Metoprolol and its -Hydroxide Metabolite in Serum by Reversed-Phase High- Performance Liquid ChromatographyJournal of Chromatographic Science, 1989
- Simultaneous Determination of Metoprolol and α-Hydroxymetoprolol in Human Plasma and Urine by Liquid Chromatography with a Preliminary Observation on Metoprolol Oxidation in Japanese SubjectsTherapeutic Drug Monitoring, 1988
- Determination of metaprolol and two major metabolites in plasma and urine by column liquid chromatography and fluorometric detectionJournal of Chromatography B: Biomedical Sciences and Applications, 1987
- Analysis of α-hydroxy metabolites of metoprolol in human urine after phosgene/trimethylsilyl derivatizationJournal of Mass Spectrometry, 1987