Indole Affects Biofilm Formation in Bacteria
- 1 October 2010
- journal article
- Published by Springer Science and Business Media LLC in Indian Journal of Microbiology
- Vol. 50 (4), 362-368
- https://doi.org/10.1007/s12088-011-0142-1
Abstract
Biofilm is bacterial population adherent to each other and to surfaces or interfaces, often enclosed by a matrix. Various biomolecules contribute to the establishment of biofilms, yet the process of building a biofilm is still under active investigation. Indole is known as a metabolite of amino acid tryptophan, which, however, has recently been proved to participate in various aspects of bacterial life including virulence induction, cell cycle regulation, acid resistance, and especially, signaling biofilm formation. Moreover, indole is also proposed to be a novel signal involved in quorum sensing, a bacterial cooperation behavior sometimes concerning the biofilm formation. Here the signaling role and molecular mechanism of indole on bacterial biofilm formation are reviewed, as well discussed is its relation to bacterial living adaptivity.Keywords
This publication has 63 references indexed in Scilit:
- Bacterial charity work leads to population-wide resistanceNature, 2010
- Flow-Based Microfluidic Device for Quantifying Bacterial Chemotaxis in Stable, Competing GradientsApplied and Environmental Microbiology, 2009
- Vibrio biofilms: so much the same yet so differentTrends in Microbiology, 2009
- Insights on Escherichia coli biofilm formation and inhibition from whole‐transcriptome profilingEnvironmental Microbiology, 2009
- Impact of the RNA Chaperone Hfq on the Fitness and Virulence Potential of Uropathogenic Escherichia coliInfection and Immunity, 2008
- Structure and Function of the Escherichia coli Protein YmgB: A Protein Critical for Biofilm Formation and Acid-resistanceJournal of Molecular Biology, 2007
- EnterohemorrhagicEscherichia coliBiofilms Are Inhibited by 7-Hydroxyindole and Stimulated by IsatinApplied and Environmental Microbiology, 2007
- Signal Mimics Derived from a Metagenomic Analysis of the Gypsy Moth Gut MicrobiotaApplied and Environmental Microbiology, 2007
- YliH (BssR) and YceP (BssS) Regulate Escherichia coli K-12 Biofilm Formation by Influencing Cell SignalingApplied and Environmental Microbiology, 2006
- Factor Fraction required for the Synthesis of Bacteriophage Qβ-RNANature, 1968