The sensitizing potency of Euxyl® K 400 and its components 1,2‐dibromo‐2,4‐dicyanobutane and 2‐phenoxyethanol
- 1 March 1993
- journal article
- Published by Wiley in Contact Dermatitis
- Vol. 28 (3), 149-153
- https://doi.org/10.1111/j.1600-0536.1993.tb03376.x
Abstract
Using a modified FCA (Freund's complete adjuvant) procedure, the sensitizing capacity of Euxyl K 400 and its ingredients, 1,2-dibromo-2,4-dicyanobutane and 2-phenoxyethanol, has been studied in guinea pigs. The experiments demonstrate that a distinct but weak sensitizing potency exists for Euxyl K 400 and dibromodicyanobutane. Phenoxyethanol remained almost negative. These results are in good accordance with the low number of cases of allergic contact dermatitis due to Euxyl K 400 and dibromodicyanobutane described since their introduction on the market. Cases of phenoxyethanol contact allergy have been published hitherto only 4x in the medical literature.Keywords
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