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Figure S2 from Resistance to Pyrrolobenzodiazepine Dimers Is Associated with SLFN11 Downregulation and Can Be Reversed through Inhibition of ATR
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Figure S2 from Resistance to Pyrrolobenzodiazepine Dimers Is Associated with SLFN11 Downregulation and Can Be Reversed through Inhibition of ATR
Figure S2 from Resistance to Pyrrolobenzodiazepine Dimers Is Associated with SLFN11 Downregulation and Can Be Reversed through Inhibition of ATR
SM
Shenlan Mao
Shenlan Mao
RC
Raghothama Chaerkady
Raghothama Chaerkady
WY
Wen Yu
Wen Yu
GD
Gina D’angelo
Gina D’angelo
AG
Andrew Garcia
Andrew Garcia
HC
Hong Chen
Hong Chen
AB
Allison M. Barrett
Allison M. Barrett
SP
Sandrina Phipps
Sandrina Phipps
RF
Ryan Fleming
Ryan Fleming
Sonja Hess
Sonja Hess
JK
Jens-Oliver Koopmann
Jens-Oliver Koopmann
ND
Nazzareno Dimasi
Nazzareno Dimasi
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3 April 2023
other
Published by
American Association for Cancer Research (AACR)
https://doi.org/10.1158/1535-7163.22521297
Abstract
The addition of the ATR inhibitor, AZD6738, did not show synergistic cytotoxicity with SG3199 or ADCs in parental MDA-MB-361 cells
Keywords
PYRROLOBENZODIAZEPINE
FIGURE
DIMERS
SLFN11
ADCS
MDA
REVERSED
AZD6738
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Open Access