Integration of Functional Magnetic Resonance Imaging Supported by Magnetoencephalography in Functional Neuronavigation
- 1 June 1999
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Neurosurgery
- Vol. 44 (6), 1249-1256
- https://doi.org/10.1097/00006123-199906000-00044
Abstract
In this study, the intraoperative visualization of functional data provided by functional magnetic resonance imaging (fMRI) and magnetoencephalography (MEG) leading to functional neuronavigation is demonstrated in surgery around the motor strip. In seven patients with lesions adjacent to the central region, fMRI was performed with a 1.5-Tesla magnetic resonance system, using axial echo-planar imaging with a motor and a sensory task. Somatosensory and motor evoked fields were recorded with a biomagnetometer. fMRI and MEG were matched to an anatomic three-dimensional magnetic resonance image set by a contour fit. Then this three-dimensional image data set was transferred to the navigation microscope and displayed in the eyepieces of the microscope during surgery. Additionally, intraoperative recording of somatosensory evoked potentials was performed for verification of the central sulcus. In all cases, the projection of fMRI and MEG data into the operating viewing field allowed easy identification of the central region, which was confirmed by phase reversal of somatosensory evoked potentials in each case. fMRI and MEG measurements yielded corresponding results in each patient. Functional neuronavigation with integration of fMRI and MEG allows the fast identification of eloquent brain areas. The widespread availability of fMRI will result in a broad availability of functional neuronavigation, which will, in turn, contribute to the successful surgery of lesions in eloquent brain areas with lower morbidity.Keywords
This publication has 38 references indexed in Scilit:
- Magnetoencephalography may help to improve functional MRI brain mapping.European Journal of Neuroscience, 1997
- AFNI: Software for Analysis and Visualization of Functional Magnetic Resonance NeuroimagesComputers and Biomedical Research, 1996
- Functional Magnetic Resonance Imaging of Regional Brain Activity in Patients with Intracerebral Gliomas: Findings and Implications for Clinical ManagementNeurosurgery, 1996
- Functional MR and PET imaging of rolandic and visual cortices for neurosurgical planningJournal of Neurosurgery, 1995
- Mapping Function in the Human Brain with Magnetoencephalography, Anatomical Magnetic Resonance Imaging, and Functional Magnetic Resonance ImagingJournal Of Clinical Neurophysiology, 1995
- Presurgical localization of functional cortex using magnetic source imagingJournal of Neurosurgery, 1995
- Real‐Time Functional Magnetic Resonance ImagingMagnetic Resonance in Medicine, 1995
- Comparison of functional magnetic resonance imaging with positron emission tomography and magnetoencephalography to identify the motor cortex in a patient with an arteriovenous malformationJournal of Image Guided Surgery, 1995
- Sensory motor cortex: correlation of presurgical mapping with functional MR imaging and invasive cortical mapping.Radiology, 1994
- Processing strategies for time‐course data sets in functional mri of the human brainMagnetic Resonance in Medicine, 1993