Effect of age on the endothelial cell count in the normal eye.

Abstract

The endothelial cell count was studied in 275 normal [human] eyes. A gradual decline to the age of 50 yr was shown with no appreciable difference thereafter. Review of earlier reports of progressive reduction throughout life indicates that a different interpretation is likely, which conforms with the results of this and other studies. The value of detailed endothelial studies is briefly discussed.