AMINO ACID COMPOSITION AND SEQUENCE OF DERMORPHIN, A NOVEL OPIATE‐LIKE PEPTIDE FROM THE SKIN OF PHYLLOMEDUSA SAUVAGEI
- 1 March 1981
- journal article
- Published by Wiley in International Journal of Peptide and Protein Research
- Vol. 17 (3), 275-283
- https://doi.org/10.1111/j.1399-3011.1981.tb01993.x
Abstract
Dermorphin, a heptapeptide with very potent opiate-like activity, has been isolated from methanol extracts of the skin of the South American frog Phyllomedusa sauvagei. The amino acid sequence of the peptide is: H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2. Dermorphin presents striking differences from the known enkephalins; it offers a surprising example of a peptide from Vertebrata containing a D-amino acid residue in its sequence.Keywords
This publication has 36 references indexed in Scilit:
- A novel analgesic dipeptide from bovine brain is a possible Met-enkephalin releaserNature, 1979
- α-Neo-endorphin: A “big” leu-enkephalin with potent opiate activity from porcine hypothalamiBiochemical and Biophysical Research Communications, 1979
- Separation of prolyl 3-hydroxylase and 4-hydroxylase activities and the 4-hydroxyproline requirement for synthesis of 3-hydroxyprolineBiochemical and Biophysical Research Communications, 1977
- Identification of two related pentapeptides from the brain with potent opiate agonist activityNature, 1975
- Sequence Analysis of Fluorescamine‐Stained Peptides and Proteins Purified on a Nanomole ScaleEuropean Journal of Biochemistry, 1974
- Attempts to Map a Process Evolution of Peptide BiosynthesisScience, 1971
- Chemical studies on methionyl-tRNA synthetase from Escherichia coliJournal of Molecular Biology, 1970
- Identification of Site in Triose Phosphate Isomerase Labelled by Glycidol PhosphateNature, 1970
- Über Peptidsynthesen, 31. Chromatographische Trennung einiger diastereomerer Dipeptide und Betrachtungen zur KonformationEuropean Journal of Inorganic Chemistry, 1965
- Spectrophotometric Titration of Tyrosine Residues of Beef Heart Cytochrome c.Acta Chemica Scandinavica, 1964