TRP Channel Knockout Mice Lose Their Cool
- 3 May 2007
- journal article
- editorial
- Published by Elsevier BV in Neuron
- Vol. 54 (3), 345-347
- https://doi.org/10.1016/j.neuron.2007.04.025
Abstract
Heat and cold transduction by peripheral sensory neurons is a fundamental step in the avoidance of dangerous thermal extremes. In this issue of Neuron, Dhaka et al. and Colburn et al. report that mice lacking the cold- and menthol-gated ion channel TRPM8 exhibit deficient behavioral responses to cold temperatures.Keywords
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