Synthesis and Fungicidal Activity against Rhizoctonia solani of 2-Alkyl (Alkylthio)-5-pyrazolyl-1,3,4-oxadiazoles (Thiadiazoles)
- 21 October 2000
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Agricultural and Food Chemistry
- Vol. 48 (11), 5312-5315
- https://doi.org/10.1021/jf991065s
Abstract
Some series of 2-alkyl (alkythio)-5-((4-chloro)-3-ethyl-1-methyl-1H-pyrazole-5-yl)-1,3,4-oxadiazoles (thiadiazoles) were prepared as potential fungicides. Their fungicidal activity was evaluated against rice sheath blight, which is a major disease of rice in China. Structure−activity relationships for the screened compounds were evaluated and discussed. It was found that 5-(4-chloro-3-ethyl-1-methyl-1H-pyrazole-5-yl)-1,3,4-thiadiazole-2-thione has the higher fungicidal activity. Keywords: Pyrazolyl-1,3,4-oxadiazole; pyrazoly1-1,3,4-thiadiazole; fungicide; rice sheath blight; Rhizoctonia solaniThis publication has 1 reference indexed in Scilit:
- SYNTHESIS, ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY OF SOME NEW 1,3,4-OXADIAZOLES AND 2-SUBSTITUTED AMINO-L,3,4-OXADIAZOLE DERIVATIVES CONTAINING BENZIMIDAZOLE MOIETYBulletin of Pharmaceutical Sciences. Assiut, 1994