Phytochemicals in thyroid cancer: analysis of the preclinical studies
- 15 February 2021
- journal article
- review article
- Published by Springer Science and Business Media LLC in Endocrine
- Vol. 73 (1), 8-15
- https://doi.org/10.1007/s12020-021-02651-y
Abstract
Purpose In the search for novel effective compounds to use in thyroid cancer (TC) unresponsive to current treatment, attention has recently focused on plant-derived compounds with anticancer activity. In this review, we discuss the preclinical studies demonstrating phytochemical activity against thyroid cancer cells. Results/Conclusions In particular, we describe their antiproliferative properties or ability to re-induce iodine retention, thus supporting their potential use as single agents or adjuvants in radioiodine-resistant thyroid cancer treatment.Keywords
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