Regioselective Palladium Cross-Coupling of 2,4-Dihalooxazoles: Convergent Synthesis of Trisoxazoles
- 12 March 2008
- journal article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 73 (8), 3303-3306
- https://doi.org/10.1021/jo800121y
Abstract
A regioselective Suzuki−Miyaura cross-coupling of 2,4-dihalooxazoles followed by a Stille coupling has been successfully developed. The procedure affords convergent syntheses of trisoxazoles in high yield and in a minimum number of steps.Keywords
This publication has 8 references indexed in Scilit:
- Iterative two-step strategy for C2–C4′ linked poly-oxazole synthesis using Suzuki–Miyaura cross-coupling reactionTetrahedron Letters, 2007
- Suzuki Coupling of OxazolesOrganic Letters, 2006
- Synthesis of the Eastern Portion of Ajudazol A Based on Stille Coupling and Double Acetylene CarbocuprationOrganic Letters, 2005
- Regioselective cross-coupling reactions of multiple halogenated nitrogen-, oxygen-, and sulfur-containing heterocyclesTetrahedron, 2004
- Amaryllidaceae, Sceletium, imidazole, oxazole, thiazole, peptide and miscellaneous alkaloidsNatural Product Reports, 2002
- Air-Stable Trialkylphosphonium Salts: Simple, Practical, and Versatile Replacements for Air-Sensitive Trialkylphosphines. Applications in Stoichiometric and Catalytic ProcessesOrganic Letters, 2001
- Copper-Mediated Cross-Coupling of Organostannanes with Organic Iodides at or below Room TemperatureJournal of the American Chemical Society, 1996
- Bioactive marine metabolites. Part 13. Kabiramide C, a novel antifungal macrolide from nudibranch eggmassesJournal of the American Chemical Society, 1986