Lysine-specific demethylase 1 promotes the stemness and chemoresistance of Lgr5+ liver cancer initiating cells by suppressing negative regulators of β-catenin signaling
- 20 April 2015
- journal article
- research article
- Published by Springer Science and Business Media LLC in Oncogene
- Vol. 34 (24), 3188-3198
- https://doi.org/10.1038/onc.2015.129
Abstract
No abstract availableKeywords
This publication has 51 references indexed in Scilit:
- ADAR1 is essential for intestinal homeostasis and stem cell maintenanceCell Death & Disease, 2013
- Lgr5-Expressing Cells Are Sufficient and Necessary for Postnatal Mammary Gland OrganogenesisCell Reports, 2013
- The Histone Demethylase KDM1A Sustains the Oncogenic Potential of MLL-AF9 Leukemia Stem CellsCancer Cell, 2012
- Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemiaNature Medicine, 2012
- LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cellsNature, 2011
- LSD1 Is a Subunit of the NuRD Complex and Targets the Metastasis Programs in Breast CancerCell, 2009
- EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell FeaturesGastroenterology, 2009
- Identification of stem cells in small intestine and colon by marker gene Lgr5Nature, 2007
- LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcriptionNature, 2005
- Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog LSD1Cell, 2004