Elevated profile of Th17, Th1 and Tc1 cells in patients with immune thrombocytopenic purpura

Abstract
T-lymphocyte abnormalities are considered important in the pathogenesis of chronic immune thrombocytopenic purpura (ITP). Both CD4+ (Th) and CD8+ (Tc) T lymphocytes can be functionally divided into type 1 (T1) and type 2 (T2) subsets based on the secretion of cytokines. Since Semple[1][1] discovered