Pituitary cyst presenting with hyponatremia and increased secretion of brain natriuretic peptide
- 1 December 2005
- journal article
- case report
- Published by Journal of Neurosurgery Publishing Group (JNSPG) in Journal of Neurosurgery
- Vol. 103 (6), 1092-1094
- https://doi.org/10.3171/jns.2005.103.6.1092
Abstract
In most cases of pituitary cyst there are no clinical symptoms and the lesions are found incidentally. The authors report the case of a 60-year-old man with a pituitary cyst causing visual disturbance and hyponatremia. The patient presented with appetite loss and general fatigue. On admission, blood workup showed severe hyponatremia (112 mEq/L), and bitemporal hemianopsia was observed on neurological examination. Magnetic resonance imaging revealed an intra- and suprasellar region cystic mass extending to the frontal base and hypothalamic area. The serum level of brain natriuretic peptide (BNP) was elevated (92 pg/ml) with polyuria and excessive Na excretion. Transsphenoidal surgery was performed to drain the cyst. The cyst wall was partially excised and the cystic fluid was aspirated. The secretion of BNP normalized postoperatively, and the hyponatremia and visual symptoms resolved. Histological examination, including an electron microscopy study, confirmed the diagnosis of a simple cyst. This appears to be the first reported case of a pituitary simple cyst associated with hyponatremia and an elevated BNP level.Keywords
This publication has 10 references indexed in Scilit:
- Brain Natriuretic Peptide and Cerebral Vasospasm in Subarachnoid HemorrhageStroke, 2000
- Natriuretic PeptidesThe New England Journal of Medicine, 1998
- Secretion of brain natriuretic peptide in patients with aneurysmal subarachnoid haemorrhageThe Lancet, 1997
- Human brain natriuretic peptide-like immunoreactivity in human brainPeptides, 1992
- Atrial natriuretic factor and salt wasting after aneurysmal subarachnoid hemorrhage.Stroke, 1991
- Suprasellar and intraventricular blood predict elevated plasma atrial natriuretic factor in subarachnoid hemorrhage.Stroke, 1991
- Transsphenoidal treatment of non-neoplastic intrasellar cystsJournal of Neurosurgery, 1984
- Benign intrasellar cystsSurgical Neurology, 1981
- Cysts of sellar and pharyngeal hypophysesPathology, 1971
- On the presence of cysts in the human pituitaryThe Anatomical Record, 1949